Extracellular chromatin traps interconnect cell biology, microbiology, and immunology
Darrah and Andrade present an analytical comparison of different modes of cell death and contrast the potential contributions of apoptosis, necrosis, and NETosis to the release of nuclear autoantigens. The large number of autoantigens that are integral components of NETs provide a compelling argument for NETosis' role in the pathogenesis of autoimmune disorders and the β