In many cases, the harmful environmental effects of pig farm effluents are caused by the high concentration of animals in a limited area and the defective management of the wastes produced. This paper presents the study of the effectiveness of the hybrid pilot, and evaluates the influence of design and operational parameters on treatment efficiency →
In 2015, metabolism is the heart of an ever growing body of studies, spanning the fields of cancer, stem cells, and, as highlighted in this series of review articles, immunology and metabolic diseases. In particular, the roles of intermediates of metabolism in the control of gene expression, of metabolic enzymes in the regulation of protein →
Editorial on the Research Topic Functional Testing of Vestibular Function The vestibular ocular reflex is responsible for stabilizing the eyes in space and the body in space during head motion. Using the novel functional head impulse test, Romano et al.report that athletes of different sports have different gaze stabilization performances when tested at the highest →
The aim of this paper is to study the educational and occupational achievement of members of second-generation ethnic minority groups in England, whether they are subject to similar class effects as those from the majority group, and whether there are specific ethnic penalties in their educational trajectory from compulsory schooling to higher education and →
In this study, we aim to evaluate the prevalence of fatigue and the factors associated with fatigue among patients with axSpA within an Asian population. In the PCA, disease activity and impact variables were associated with both measures of fatigue, and disease chronicity was additionally associated with SF-36 VT.
With comparisons to the current CO 2 atmosphere concentrations, the objectives of the present study were to address how daytime and/or nighttime eCO 2 could affect: mulberry biomass production, leaf concentrations of macronutrients and micro-nutrients, and leaf concentrations of carbohydrates and N-containing compounds. Based on the on-site variation of daytime and nighttime atmosphere CO 2 →
Over the past 5 years, a number of studies on board games and digital games have suggested that approaches such as the gamification of therapeutic processes or casual games used for therapeutic purposes have the potential to promote cognitive and behavioral change and improvements in symptoms. For example, the game called " Let's Face It!" →
Editorial on the Research Topic Exploring the Frontiers of Regenerative Cardiovascular Medicine In this special issue of Frontiers in Cardiovascular Medicine, we assembled a collection of original research articles, reviews, a case report and a perspective within an over-arching theme of " Exploring the Frontiers of Regenerative Cardiovascular Medicine". Though the adventitia is known to →
This paper is a survey on the potential and properties of nanomaterials and microbial compounds in improving the process of wound and scar healing. Immediately after the injury, the complicated process of healing begins, which is involved of several steps including hemorrhage, coagulation, acute inflammation, the proliferation of connective tissue and parenchyma cells, synthesis of →
To date, dopamine-replacement therapy is the first choice of treatment to lessen the impact of motor and non-motor symptoms, however DRT does not prevent progressive disabilities and does not change the course of the disease. The structure of music may aid in synchronization with the rhythm compared to the isochronous beat of a metronome.
As it was seen in the previous section that these cationic peptides tend to bind strongly to anionic lipids, it seems reasonable to assume that at least some of the peptides are located in the membrane in a -stranded conformation. In a study of KL peptides with 6 26 amino acids, hemolytic activity was low →
In a landmark study, Hashimoto and colleagues discovered the presence of a substantial amount of d -serine in the rodent brain. Given the contribution of d -serine to LTP, and the fact that LTP is considered a key mechanism underlying learning and memory, it was no surprise when studies confirmed the importance of d →
The elevation of the terrain is high in the northwest and low in the southeast, forming a slope from the northwest to the southeast. The pH of the Minghu Wetland sediments and the concentration of each heavy metal in the samples are presented in Table 3.
In this study, we investigated the effect of the consumption of green tea, a common beverage in Japan, on the abundance of FP in the gut of mice. Following confirmation that the administration of green tea increases the abundance of FP in the gut microbiota, the physiological effects of FP were investigated in an IBD →
The main objective of the current review article is to overview the effects of bariatric surgery on the overall and various types of CVD. Nonetheless, in a recent study of patients with obesity and AF who underwent bariatric surgery, the risk of AF-related acute care use transiently increased for a few months after the surgery.
To date, more than 300 disease associated genes have been implicated in the pathogenesis of the disease, most of which are involved in the development and normal function of photoreceptor and cells from the retinal pigment epithelium. FP of the index patient with peripheral nummular spicule deposits and atrophy.
First of all we can establish that a healthy lifestyle by following a good diet, sleeping well and exercising. Furthermore, there is another aspect of healthy living that should be sleeping well for the most part we all consider sleep as a good thing to do, but we do not really know how this activity →
J, and Schorey, J.S. M, and Jentzen, J.M.
That the sense of agency can be elicited in neurosurgical patients in the absence of bodily movements seemingly suggests that the outcome is not strictly needed for the sense of agency and the related experience of intending to act to arise. In the philosophy of action, there is a widespread agreement that intentional actions are →
Editorial on the Research Topic Mathematical Modeling of the Immune System in Homeostasis, Infection and Disease The immune system is a dynamic and multi-level biological system that protects host organisms against invading pathogens and tumor development, and plays an active role in tissue homeostasis and organ regeneration. Shifting this simplistic perception of the immune system →
As the philosophical analysis of this paper shows, if advocates of Open Science promote the openness of publicly funded research to foster, at least in part, new business opportunities and joint private-public ventures, as well as new markets for the development of online information and communication technologies, then Open Science ends up contributing to furthering →
Not only is this broadly relevant to the origin of novel functions via a number of pathways in which duplication plays a role, it is specifically relevant to the evolution of venom, as many important toxins are members of gene families which have expanded through duplication. Once the role of context in influencing the function →
In the k -th layer, the weighted sum of inputs y k 1 is denoted as z k, the bias as b k, the activation function as f k and its derivative as f k , with k [1, K ], k , and K the number of layers. We demonstrate both theoretically and experimentally →
DMD is caused by the lack of dystrophin which is a protein that provides stability to the sarcolemma and is likely involved in the transmission of force between the extracellular matrix and the intracellcular contractile apparatus. J, and Bemben, M.G.
The relative easy access to the antimicrobials and also the massive employment of these compounds for industrial purposes, including food production, have both strongly contributed to the progressive increase of resistant microorganisms. In other words, nature is a generous source of compounds, with the potential to treat diseases, including infectious diseases.
This tendency was generalized in the majority of the European countries and also in the United States of America, with the replacement of the old broader concept by a newer and narrower concept of delusion as a disorder of thought content. In this article, we intend to review the main aspects related to the theory →
Mice in the CP and baicalin groups were injected intraperitoneally with cerulein to induce CP, and the same volume of sterilized physiological saline was injected into the control mice. After dehydration, paraffin embedding, and sectioning of the pancreas, hematoxylin and eosin and Masson staining protocols were carried out according to the method in the manual →
This special issue on " Current MEG Research in Psychiatry" provides a state-of-the-art overview of the potential and scope of MEG, ranging from recent developments in MEG methods to the study of cognitive and sensory dysfunctions in ASD and SZ including functional connectivity in psychosis, to the role of alterations nervous system activity in major →
Critical Issue in Global Health: Bill Nye in his video about poverty clearly suggests that poverty is not an issue which does not have any solution. Duflo also suggests the same idea as offered by Nye in her ted talk that there is not much change made by foreign aid which is why poverty is →
Whilst the risk posed by DBS for movement disorders is generally deemed to be acceptably low, the potential risk of surgical complications and non-compliance may be exacerbated in the context of DBS treatment SE-AN, due to patients' severe chronic malnutrition. However, the justification for this claim is that reversibility and adjustability are particularly valuable in →
Editorial on the Research Topic Natural Killer Cells in Tissue Compartments Most of our current knowledge about human natural killer cells comes from studies on cells derived from peripheral blood, also known as " conventional" NK cells, but recently, interest in the characterization of NK cells within tissues has increased, and besides recirculating cells, different →
Editorial on the Research Topic Recurrence Analysis of Complex Systems Dynamics In the last three decades, recurrence plot and quantification techniques have become important research tools in the analysis of short, noisy, and non-stationary data. To better understand complex systems and the origin of recurrences, it is important to understand the coupling between sub-units in →
The purpose of this study is to identify one or several potential biomarkers of the immune modulation developed by vitD3-tolDC over T cells, which could constitute an interesting tool for the monitoring of patients treated with these cells in clinical trials, and the understanding of the mechanisms of tolerance induction. 1 g/ml of the whole →
There are other T RM cells in the lungs with different roles, including T RM cells that may cause pathological immune responses and tumor-infiltrating T RM cells that can enhance anti-tumor immunity in the lungs. Compared with CD8+ T cells, CD4+ T cells enter the lung tissues first and direct the localization of CD8+ T →
A, and Meaney, M.J. J, Widdig, A, and Gerald, M.S.
The scope of the present research topic " Neural circuits underlying emotion and motivation: Insights from optogenetics and pharmacogenetics " is to provide a panoramic view of recent progress in this direction, with special emphasis on circuit level exploration of emotion, motivation and memory. Identification and optogenetic manipulation of memory engrams in the hippocampus.
Since the widespread use of the bench press as a basic exercise for developing upper body strength and power output, the aim of the present study was to evaluate the effects of contrast movement tempo on power output and bar velocity during the bench press exercise. The experiment was performed following a randomized crossover design, →
Moreover, empirical studies have pointed out the unique relationship between the CM and the severity of depressive symptoms in OCD. Since the specific relationship between CM and symptoms of OCD is poorly understood, we performed the meta-analysis to quantify the magnitude and significance of correlations between CM and OCS severity in patients with OCD and →
The greater the belief of and risk to adversaries that they will be identified, apprehended, and prosecuted either through legal or policy decisions, the more likely this will be factored in the decisions and choices they make. In the years prior to the U.S.program's creation, laws were enacted to enhance the prosecution of the unauthorized →
Studies of meditation practices not related to a particular religious or spiritual tradition still provide information that may contribute to the overall study of religious and spiritual phenomena, but that is not the focus of this paper. As someone who has studied the neurophysiology of a variety of practices with both spiritual and non-spiritual goals, →
As dopamine was reported to be involved in the pathophysiology of mania in the 1970s and as changes in dopaminergic neurotransmission have consistently been reported in bipolar disorders, the question of the antimanic properties of antidopaminergic drugs such as antipsychotics is a fair one. J Affect Disord 13: 14 9.doi: 10.
Am J Psychiatry 172: 760 7.doi: 10. EGEMS 2: 1049.doi: 10.
The appearance of data silos and cloud computing storage all facilitate the use of big data. Those vast amounts of mixture data bring challenges: the lack of data standardization, the concern of privacy and security issues, the speed-limitation and eavesdrop possibility of data transfer, the reliability of data storage, etc.
A Commentary on Acute Effects of Exercise Mode on Arterial Stiffness and Wave Reflection in Healthy Young Adults: A Systematic Review and Meta-Analysis by Pierce, D. 00073 We read with great interest the commentary and concerns raised by Kingsley and Tai regarding the proposed inaccurate use of data from their manuscript in our systematic review →
This macro-trend is likely to influence the key policies in the health sector as well as national policy goals aimed at improving the living standards of the people. Child health which focuses on infant mortality rate is regarded as a very vital macro-trend in the United States that requires a lot of attention so as →
Specifically, priming has been found to be a valid technique for influencing the non-conscious activation of implicit autonomous and controlled motives. In addition to the content of motivation at the reflective level, other conscious processes may also be influenced implicitly.
All this was the substance of our paper published last year which necessitates the possibility of integration of a positive strand RNA virus genome into the host genome as a starting premise. The current paradigm is that DNA transcribed from the RNA of these viruses does not exist in the host genome; and it requires →
The first type of post-Covid consequences are directly related to organ damage in the acute phase, either due to the viral infection and the ensuing inflammatory response, or the complications of treatment in the intensive care setting. Another study by Raman et al.describes persistent MRI abnormalities seen in the lungs and the heart of COVID-19 →
9 % in total of cases. 2 % respectively with total recordable cases of 0.
The next section recounts the recent history of attention to the security implications of the life sciences, with particular reference to the identification and assessment of " research of concern" and related designations. Through the sorts of initiatives mentioned in the previous paragraphs emerged a sense of the potential security implications of the life science →
This all impacts on clinicians' ethical responsibilities, as it may be possible to provide DBS in ways which are clinically equivalent, but have varied outcomes in terms of patients' personality and behavioral changes. They should monitor refusals of DBS treatment and assess how autonomous patients' choices over post-DBS settings are in relation to undue influence →
A review of the effects of physical activity and exercise on cognitive and brain functions in older adults.J. The effect of acute and chronic exercise on cognitive function and academic performance in adolescents: a systematic review.J.Sci.Med.
A commentary on Nojima, J, Iwatani, Y, Suehisa, E, Kuratsune, H, and Kanakura, Y. Nojima, J, Kuratsune, H, Suehisa, E, Kitani, T, Iwatani, W, and Kanakura, Y.
Editorial on the Research Topic Inflammation in the CNS: Advancing the Field Using Intravital Imaging Inflammation of the central nervous system contributes to a diverse array of life-threatening and debilitating conditions. Particularly, the advent of two-photon intravital microscopy has allowed researchers to directly examine the role of multiple immune cell populations in the initiation and →
FIGURE 2 The whole gene expression value of low and high-peak bone mass samples was analyzed using GSEA software. TABLE 2 The hub genes for DEGs in monocytes of LPBM.
Cunnea and Stronach review the currently available immortalized cell lines in the context of sensitivity and resistance to platinum and highlight deficiencies in in vitro development of treatment resistance. BRCA and early events in the development of high grade serous ovarian cancer.
A Corrigendum on Genome Sequencing and Comparative Analysis of Three Hanseniaspora uvarum Indigenous Wine Strains Reveal Remarkable Biotechnological Potential by Guaragnella, N, Chiara, M, Capece, A, Romano, P, Pietrafesa, R, Siesto, G, et al. 10: 3133.doi: 10.
Modelling Past and Present Agglomerations to Understand Urban Ways of Life Urbanism in the past and present remains hotly debated in academia and the media. The long-term trajectory of Rome is quite well-known and established from the early supremacy within Latium vetus in pre-historic and early historic times, to the emerging power in Italy, during →
The greatest fermentor in the human body is the post-esophageal gut; the anaerobic environment is capable of producing an environment where gases may be formed, both in the foregut, through the small intestines, and in the hindgut, with the gradient of bioreactor activity increasing in that order. Rather, the polygenic deregulation of smooth muscles functions →
Together with the increase in transparency and sharing of performance metrics, it has been suggested that performance and physiological biometrics may strengthen the sensitivity and applicability of the Athlete Biological Passport in the fight against doping. Knowledge is power: issues of measuring training and performance in cycling.J.
Specifically, we investigated the 1) recovery of N; 2) changes in the physical and chemical properties of the drying substrate; and, 3) the elemental composition of the end-products. This was done to assess the effect of high pH at the start of the treatment on the recovery of N from urine.
Editorial on the Research Topic BODIPYs and Their Derivatives: The Past, Present and Future Over the past decades, boron-dipyrromethene fluorescent dyes, first described by Treibs and Kreuzer, have been the focus of considerable research interest and rapidly growing. The triplet excited state of bodipy: formation, modulation and application.Chem.Soc.Rev.
The study aimed to examine the implicit attitudes of smokers and non-smokers towards smoking, as reflected both in the behavioral data and in electroencephalography potentials during the GNAT. Gajewski and Falkenstein have reported, in a Go/NoGo task, that the latency but not the amplitude of the NoGo N200 is susceptible to task complexity, and infer →
Introduction Background of the Study: We chose this project because a mosquito coil made up from natural mosquito repelling plants will remove the health problems caused by commercial mosquito repellents.oregano and lemongrass are easy to find and very common and also if this project succeed this can be profitable for business and can encourage others →
However, the F.D.A.stills deems amalgam fillings safe for adults and children over six, leaving the general public with the question, " Do amalgam fillings pose a significant threat to human health? " Since the F.D.A.eemed amalgam fillings safe for the public, many people hold the view that the mercury used in dental fillings is safe →
However, to date there is no reliable means to discriminate between the absence of rejection due to the effects of conventional immunosuppression and the absence of rejection due to the successful induction of an active process of tolerance. In experimental transplantation models, the number of cells and the mechanisms involved in tolerance are numerous and →
Editorial on the Research Topic Innate Immunity in the Context of Osteoimmunology The term " osteoimmunology" identifies the research field aimed at studying the crosstalk between cells of the skeletal and immune systems. The close relationship between these two systems is apparent based on the sharing of the same microenvironment, but it also extends beyond →
Types of Healthcare Wastes affiliations Types of Healthcare Wastes The different types of wastes in healthcare are in different categories. Another type of waste is hazardous wastes which according to WHO arise from contamination of drugs.
In conditions of energy excess, the white adipose tissue accumulates fat in the form of triglycerides, whilst brown adipose tissue has the potential stimulate energy expenditure by dissipation of fat to produce heat and maintain body temperature. Thus, chronic treatment with rosiglitazone promotes the expression of brown fat genes, mitochondriogenesis, and thermogenesis capacity in a →
The most prominent of these are the extent to which we are explicitly aware of the basis of such decisions; the biasing influence of pre-existing emotional labels in complex decision making; and the extent to which EBL systems are anatomically and functionally independent of episodic memory systems. An important element in our understanding of the →
The conference emphasized that it is important to adhere to the principle of " Taking undergraduate education as the foundation" to promote the " Four Returns," that is, a return to common sense, a return to duty, a return to original intentions, and a return to the dreams and aspirations of students, emphasizing the need →
The original phenomenological observation on the non-cytolytic HIV-suppressive activity of CD8 + T cells was made by Chris Walker and Jay Levy in the mid-80s while they were attempting to increase the rate of HIV-1 isolation from asymptomatic seropositive individuals. The LTCB was an ideal site in this respect because a major focus for over →
Aging Cell.doi: 10. 8: 4 11.doi: 10.
Parental depressive symptoms as a predictor of outcome in the treatment of child internalizing and externalizing problems. J Fam Psychol 16: 50 7.doi: 10.
D, and Turner, J.A. D, and Turner, J.A.
Opening its doors in March of 1888, the Training School in Vineland was considered to be the third institution of its kind; the first opened in Massachusetts in 1848 and the second in New York in 1852. From One Century to the Next: A History of Wrentham State School and the Institutional Model in Massachusetts.
The worldwide burden of sepsis in pediatric intensive care in terms of morbidity and mortality remains high and is a key healthcare priority. Yet, in the face of many unanswered questions and associated harm, the imperative to investigate the role of FBT in sepsis exists.
In their reviews, Geginat et al.and Clausen and Stoitzner dissect the instrumental role played by specialized DC subsets in instructing protective T cell immunity, emphasizing how this specialization, conserved in mice and humans, suits at best the need of dedicated and qualitative different " classes" of T cells for immune homeostasis, defense against pathogens, and →
Because Bernard et al.presented half of the stimuli upright and the other half inverted, Schmidt and Kistemaker suggest that Bernard et al.'s findings might be due to less stimulus symmetry among inverted female bodies: If inverted female bodies are less symmetrical than upright female bodies in Bernard et al.'s setup, their findings could be explained →
Editorial on the Research Topic Diversity and Universality in Causal Cognition The capacity to acquire and use causal knowledge belongs to the central cognitive competencies that allow us to orient in the world, and this knowledge shapes our cognitive, affective, and behavioral responses. 00245 Bender, A, Beller, S, and Medin, D.L." Causal cognition and culture," →
The sharp rise in numbers of Muslims in Germany has inevitably led to a significant shift in the sociopolitical landscape within Germany and in Europe. This included questions regarding the nature of the war and conflict they fled back home, the experience of their displacement journey, and current challenges faced or experienced following their arrival →
Based on these specimens and sequences obtained from GenBank, the phylogenetic analyses and taxonomic study of Phlebiopsis and related taxa in the Phanerochaetaceae were undertaken. Notes Phlebiopsis brunnea is characterized by a coriaceous basidiomata with a smooth hymenophore and brown context, abundant, brown skeletocystidia in the subiculum and subhymenium, lamprocystidia, and oblong ellipsoid to subcylindrical →
In Parkinson's disease, DBS is a neurosurgical treatment offered to approximately 5% of patients, and consists in the permanent implantation of stimulating electrodes in deep brain structures. Overall, compared to initial models investigating the possibility of closed-loop stimulation in Parkinson's disease, the use of neural mass and neural field models represents a significant advance in →
Editorial on the Research Topic Culture, Self, and Autonomy In our special topic Culture, Self and Autonomy we have examined the complex issues relating to how self and autonomy are explored, construed, and experienced by different subjects and across cultural contexts. The notion of the self stands at the center of the discussion on psychological →
The aim of this study is to analyze the clinical pattern of pediatric patients admitted to our unit during the first 3 months of the outbreak of SARS-CoV-2 in Bergamo, following a period of unmitigated viral circulation. The patients were admitted in the first phase of the epidemic and during the lockdown, therefore we considered →
Below we place this argument in the context of research on cross-modal integration and processing experiences, and discuss some implications. Some " fringe experiences" include the feelings of familiarity and knowing, tip-of-the-tongue phenomena, and the sense of ease, rightness or coherence.
At present, 75 sRNAs have been identified in S.pyogenes and 179 sRNAs in S.pneumoniae.In S.agalactiae, 197 sRNAs were predicted in silico and 10 of them were validated by northern blot. A genome-wide analysis of small regulatory RNAs in the human pathogen group A Streptococcus.
This shift from an anthropocentric ethic to a zoocentric ethic is, in part, the result of a growing body of research demonstrating cognition, emotion, and sentience in animals once assumed to be " unfeeling" and relegated to the lower rungs of the now-obsolete " evolutionary ladder". In 2007, a year before Robertson's review was published, →
Errors that arise associated with the chromosome-spindle attachment can result in missegregation of the pair of sister chromatids into one of the two daughter cells or can cause chromosomes to lag at the middle of the dividing cell. In addition to such mechanical aspects of subcellular structures, the shape and mechanics of the entire cell →
The other surface of an epithelial bed is attached to the underlying tissue by a acellular cellar membrane composed of bantam fibres and nonliving polysaccharide stuff produced by the epithelial cells. The epithelial cells run alonging the capillaries and fibroblasts of connective tissue are quickly renewing.
Furthermore, thanks to recent discoveries about the microbial diversity of the human gut, we have started to achieve detailed insights about the composition of the bifidobacterial communities in this complex ecosystem and to understand the intricate relationship with their host as well as with the other members of the gut microbiota. The 21 articles comprising →
The systems that ultimately limit performance of the task are hotly contested, and may depend on a variety of factors including the type of task, the environment, external influences, training status of the individual and a host of psychological constructs. To explore new frontiers, we welcomed the submission of original research, review and perspective articles →
Quine proposed his famous criterion of ontological commitment " to be is to be the value of a variable," which states that we are ontologically committed to the entities that are in the range of the existential quantifier in the logical formulations of our best scientific theories. I will introduce the term cognitive metaphysics 4 →
Migration policies have been adjusted to facilitate the international students to remain, search for jobs and stimulate innovation and the economies of the home nations of their alma mater. I identify three patterns of response to COVID-19: Firstly, a policy and discourse of continued welcome and facilitation of international students, seen in for example in →
For example, responses may or may not be fast and efficient, respondents may or may not be aware of the purpose of the measure, may or may not intend particular outcomes on the measure, and may or may not be able to intentionally alter responses on the measure. This suggests that the evaluations resulting from →
Ma et al.extensively reviewed the recent advances to understand the biochemical and molecular mechanisms of plant-microbe interactions and their potential in the phytoremediation process, which may contribute significantly to the practical application of phytoremediation techniques. 1016/j.jenvman.2016.02.047