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Essay, 2 pages (350 words)

Sanguinarium chloride c20h14clno4 structure

Contents

  • Bio Activity:
Molecular Formula C 20 H 14 ClNO 4
Average mass 367. 783 Da
Density
Boiling Point
Flash Point
Molar Refractivity
Polarizability
Surface Tension
Molar Volume
  • Experimental data
  • Predicted – ACD/Labs
  • Predicted – ChemAxon
  • Experimental Physico-chemical Properties
    • Experimental Melting Point:

      281-285 °CIndofine[021845]
      285 °CBiosynthQ-100647
      240 °C (Decomposes)LabNetworkLN01295316
      281-285 °CIndofine[021845],[021845]
    • Experimental Solubility:

      10 mM in DMSOMedChem Expresshttp://www. medchemexpress. com/osthole. html, HY-N0052A
      Soluble to 10 mM in DMSOTocris Bioscience2302
  • Miscellaneous
    • Safety:

      GHS07BiosynthQ-100647
      H302BiosynthQ-100647
      P301+P312; P330BiosynthQ-100647
      WarningBiosynthQ-100647
    • Target Organs:

      Egr-1 inhibitor; VEGF inhibitorTargetMolT0129
    • Chemical Class:

      Ion PumpEU-OpenScreen[S 5890]
    • Bio Activity:

      AngiogenesisTargetMolT0129
      Egr-1; VEGFTargetMolT0129
      EnzymesTocris Bioscience2302
      Inhibitor of protein phosphatase 2C (PP2C)Tocris Bioscience2302
      Inhibitor of protein phosphatase 2C (PP2C), selective over PP1, PP2A and PP2B in vitro. Also inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) (IC50 = 10 ? M). Plant alkaloid that exhibits anti-inflammatory and antioxidant activity. Blocks cell cycle in the G1 phase; inhibits cell growth in human prostate carcinoma cells. Tocris Bioscience2302
      Inhibitor of protein phosphatase 2C (PP2C), selective over PP1, PP2A and PP2B in vitro. Also inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) (IC50 = 10 ? M). Plant alkaloid that exhibits anti-inflammatory and antioxidant activity. Blocks cell cycle in the G1 phase; inhibits cell growth in human prostate carcinoma cells. Tocris Bioscience2302
      OthersMedChem ExpressHY-N0052A
      PhosphatasesTocris Bioscience2302
      Protein Ser/Thr PhosphatasesTocris Bioscience2302
      Sanguinarine (chloride) is natural product. MedChem Expresshttp://www. medchemexpress. com/osthole. html, HY-N0052A

Predicted data is generated using the ACD/Labs Percepta Platform – PhysChem Module

No predicted properties have been calculated for this compound.

Density:
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction:
Molar Refractivity:
#H bond acceptors:
#H bond donors:
#Freely Rotating Bonds:
#Rule of 5 Violations:
ACD/LogP:
ACD/LogD (pH 5. 5):
ACD/BCF (pH 5. 5):
ACD/KOC (pH 5. 5):
ACD/LogD (pH 7. 4):
ACD/BCF (pH 7. 4):
ACD/KOC (pH 7. 4):
Polar Surface Area:
Polarizability:
Surface Tension:
Molar Volume:

Click to predict properties on the Chemicalize site

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