Essay, 2 pages (350 words)

Fexofenadine hydrochloride c32h40clno4 structure

Subject: Others

Info

Published: September 26, 2022
Updated: September 26, 2022
Language: English
Downloads: 16

Table of Contents

Experimental Melting Point:
Experimental Boiling Point:
Experimental Solubility:
Safety:
Target Organs:
Drug Status:
Compound Source:
Bio Activity:

Contents

Bio Activity:

Molecular Formula	C ₃₂ H ₄₀ ClNO ₄
Average mass	538. 117 Da
Density
Boiling Point
Flash Point
Molar Refractivity
Polarizability
Surface Tension
Molar Volume

Experimental data
Predicted – ACD/Labs
Predicted – ChemAxon
Predicted – Mcule

Experimental Physico-chemical Properties

Experimental Melting Point:
148-150 °CLKT Labs[F1895]
190-192 °CLabNetworkLN00176769
Experimental Boiling Point:
697. 3 °CLKT Labs[F1895]

Experimental Solubility:

50 mM in DMSOMedChem Expresshttp://www. medchemexpress. com/Terbutaline-sulfate. html

DMSO to 50 mM, water to 2 mg/mL, ethanol to 107 mg/mL, methanolLKT Labs[F1895]

DMSO: 50mg/mLMedChem ExpressHY-B0801A

Soluble in DMSOAxon Medchem1453

Soluble to 50 mM in DMSOTocris Bioscience2429

Miscellaneous

Safety:

5Axon Medchem1453

H303; H313; H317; H333; H334; H335; H373Axon Medchem1453

IRRITANTMatrix Scientific076066

no pictogramAxon Medchem1453

NoneLKT Labs[F1895]

P101; P102; P103; P260; P262; P263; P264; P270; P280; P304; P312; P340Axon Medchem1453

WarningAxon Medchem1453

Target Organs:
Histamine Receptor antagonistTargetMolT1470, T1470L
Drug Status:
approvedBIONET-Key OrganicsKS-1057
Compound Source:
syntheticMicrosource[01504179]

Bio Activity:

7-TM ReceptorsTocris Bioscience2429

Fexofenadine is a third-generation antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. MedChem Expresshttp://www. medchemexpress. com/Terbutaline-sulfate. html, HY-B0801A

GPCR/G proteinMedChem ExpressHY-B0801A

GPCR/G protein; MedChem ExpressHY-B0801A

H1 receptor antagonist; non-sedating antiallergic agentTocris Bioscience2429

Histamine H1 receptorTargetMolT1470, T1470L

Histamine H1 ReceptorsTocris Bioscience2429

Histamine ReceptorMedChem ExpressHY-B0801A

Histamine ReceptorsTocris Bioscience2429

NeuroscienceTargetMolT1470, T1470L

Selective histamine H1 receptor antagonist (pKi = 8. 1). Active metabolite of terfenadine that displays non-sedating antiallergic effects. Tocris Bioscience2429

Predicted data is generated using the ACD/Labs Percepta Platform – PhysChem Module

No predicted properties have been calculated for this compound.

Density:
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Vapour Pressure:
Enthalpy of Vaporization:
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Index of Refraction:
Molar Refractivity:
#H bond acceptors:
#H bond donors:
#Freely Rotating Bonds:
#Rule of 5 Violations:

ACD/LogP:
ACD/LogD (pH 5. 5):
ACD/BCF (pH 5. 5):
ACD/KOC (pH 5. 5):
ACD/LogD (pH 7. 4):
ACD/BCF (pH 7. 4):
ACD/KOC (pH 7. 4):
Polar Surface Area:
Polarizability:
Surface Tension:
Molar Volume:

Click to predict properties on the Chemicalize site

1-Click Docking
1-Click Scaffold Hop

Experimental Melting Point:

Experimental Boiling Point:

Experimental Solubility:

Safety:

Target Organs:

Drug Status:

Compound Source:

Bio Activity: