1,212
11
Essay, 2 pages (350 words)

Myelination

What is the function of myelination?- To support fast and efficient signal transduction
– Provide metabolic support to neuronsDiscuss myelination throughout lifeMyelination is a dynamic process that continues throughout life, peaking in our mid 30s.
Loss of myelin correlates with ageing and cognitive decline ONMYELINATION SPECIFICALLY FOR YOUFOR ONLY$13. 90/PAGEOrder NowWhat is the effect of social isolation on myelination? In specific areas of the CNS (inc. mPFC), social isolation causes a reduction in number of myelin sheaths per neuron, with a reduction in myelin sheath thickness. Though there is no reduction in OL number, they are have smaller and simpler processes. This correlates with impairment of learning and memory tasks in miceWhat evidence suggests that OLs are capable of dynamic myelination? In zebra fish, the first myelinated axon is the Mauthner axon. Even with the introduction of supernumary M axons, all will be appropriately myelinated. this shows that oligodendrocytes are able to produce more myelin when required as there is no change in the number of oligodendricytes

OLs which usually myelinated small caliber neurons are capable of myelinating large supernumerary M axons

Is there a restricted period when axons can regulate OL myelin production? Yes. There is a critical period (4-6 hours in a zebrafish) when a OL can produce myelin. During the point, its production can be very dynamic, however after this critical period, the mature myelinating OL cannot produce more myelin. This suggests that OLs are regularly being replenished as myelination carries on throughout life. Myelination during the critical period is affected by ErbB1 KO, however KO after the critical period has no effect. How neuronal activity alter myelin production during OL critical periods? Synapse like junctions between the axon and the OL seem to signal neural activity, thus stimulating myelin productionDescribe myelin sheath production round a single axon. The myelin is not ‘wrapped’ round the axon, rather is is formed from the inner layer, forcing the outer layers outwards. During the critical period, excess layers can be produced but these can be degraded. Trafficking of materials to the inner tongue of the myelin sheath is facilitated by thin cytoplasmic channels which are only apparent during development.

Thank's for Your Vote!
Myelination. Page 1
Myelination. Page 2
Myelination. Page 3

This work, titled "Myelination" was written and willingly shared by a fellow student. This sample can be utilized as a research and reference resource to aid in the writing of your own work. Any use of the work that does not include an appropriate citation is banned.

If you are the owner of this work and don’t want it to be published on AssignBuster, request its removal.

Request Removal
Cite this Essay

References

AssignBuster. (2022) 'Myelination'. 11 January.

Reference

AssignBuster. (2022, January 11). Myelination. Retrieved from https://assignbuster.com/myelination/

References

AssignBuster. 2022. "Myelination." January 11, 2022. https://assignbuster.com/myelination/.

1. AssignBuster. "Myelination." January 11, 2022. https://assignbuster.com/myelination/.


Bibliography


AssignBuster. "Myelination." January 11, 2022. https://assignbuster.com/myelination/.

Work Cited

"Myelination." AssignBuster, 11 Jan. 2022, assignbuster.com/myelination/.

Get in Touch

Please, let us know if you have any ideas on improving Myelination, or our service. We will be happy to hear what you think: [email protected]