Myeloperoxidase: a potential target of cyclic nitroxide(s) to ameliorate colitis in severe combined immunodeficiency (scid) mouse model
Central to Pathophysiology of IBD is the progressive bowel inflammation induced by a cell mediated response where neutrophils and monocytes are the primary immune cells infiltrating the bowl and featuring IBD. Elevated levels of MPO and 3-chloro-tyrosine have been reported in the colon and serum of IBD patients and fecal MPO is considered a marker →