Immunotherapeutic activities of a dna plasmid carrying the mycobacterial hsp65 gene (dnahsp65)
The principle of the method is based on the direct introduction of the plasmid into the tissue, allowing the expression of the target antigen and, consequently, the induction of an antigen-specific immune response. The DNA vaccination strategy has gained the spotlight due to the ease of production, the multiple forms of administration, the molecular stability, β