Library
Home/Others/Apalutamide c21h15f4n5o2s structure
1,750
24
Essay, 2 pages (350 words)

Apalutamide c21h15f4n5o2s structure

Subject: Others
Info
  • Published: December 27, 2021
  • Updated: October 9, 2022
  • Language: English
  • Downloads: 4
Table of Contents
  1. Experimental Solubility:
  2. Safety:
  3. Target Organs:
  4. Bio Activity:

Contents

  • Bio Activity:
Molecular Formula C 21 H 15 F 4 N 5 O 2 S
Average mass 477. 435 Da
Density 1. 6±0. 1 g/cm 3
Boiling Point
Flash Point
Molar Refractivity 110. 7±0. 4 cm 3
Polarizability 43. 9±0. 5 10 -24 cm 3
Surface Tension 75. 2±5. 0 dyne/cm
Molar Volume 300. 2±5. 0 cm 3
  • Experimental data
  • Predicted – ACD/Labs
  • Predicted – ChemAxon
  • Experimental Physico-chemical Properties

    • Experimental Solubility:

      DMSO 15 mg/mL Ethanol 5 mg/mLMedChem ExpressHY-16060
      Soluble in DMSOAxon Medchem1979
  • Miscellaneous

    • Safety:

      5Axon Medchem1979
      H303; H313; H317; H333; H334; H335; H373Axon Medchem1979
      no pictogramAxon Medchem1979
      P101; P102; P103; P260; P262; P263; P264; P270; P280; P304; P312; P340Axon Medchem1979
      WarningAxon Medchem1979

    • Target Organs:

      Androgen Receptor inhibitorTargetMolT2339

    • Bio Activity:

      Androgen ReceptorMedChem ExpressHY-16060
      Androgen Receptor; GABAA receptorTargetMolT2339
      ARN-509 is a selective and competitive androgen receptor inhibitor with IC50 of 16 nM, useful for prostate cancer treatment. MedChem Express
      ARN-509 is a selective and competitive androgen receptor inhibitor with IC50 of 16 nM, useful for prostate cancer treatment.; IC50 value: 16 nM; Target: androgen receptorARN-509 is an androgen receptor antagonist with potential antineoplastic activity. ARN-509 binds to AR in target tissues thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. This prevents binding to and transcription of AR-responsive genes. This ultimately inhibits the expression of genes that regulate prostate cancer cell proliferation and may lead to an inhibition of cell growth in AR-expressing tumor cells. MedChem ExpressHY-16060
      Endocrinology/ HormonesTargetMolT2339

Predicted data is generated using the ACD/Labs Percepta Platform – PhysChem Module

Density: 1. 6±0. 1 g/cm 3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1. 659
Molar Refractivity: 110. 7±0. 4 cm 3
#H bond acceptors: 7
#H bond donors: 1
#Freely Rotating Bonds: 5
#Rule of 5 Violations: 0
ACD/LogP: 1. 30
ACD/LogD (pH 5. 5): 1. 38
ACD/BCF (pH 5. 5): 6. 54
ACD/KOC (pH 5. 5): 133. 48
ACD/LogD (pH 7. 4): 1. 38
ACD/BCF (pH 7. 4): 6. 54
ACD/KOC (pH 7. 4): 133. 48
Polar Surface Area: 121 Å 2
Polarizability: 43. 9±0. 5 10 -24 cm 3
Surface Tension: 75. 2±5. 0 dyne/cm
Molar Volume: 300. 2±5. 0 cm 3

Click to predict properties on the Chemicalize site

Thank's for Your Vote!
Apalutamide c21h15f4n5o2s structure. Page 1
Apalutamide c21h15f4n5o2s structure. Page 2
Apalutamide c21h15f4n5o2s structure. Page 3
Apalutamide c21h15f4n5o2s structure. Page 4
Apalutamide c21h15f4n5o2s structure. Page 5
Apalutamide c21h15f4n5o2s structure. Page 6
Apalutamide c21h15f4n5o2s structure. Page 7
Apalutamide c21h15f4n5o2s structure. Page 8

This work, titled "Apalutamide c21h15f4n5o2s structure" was written and willingly shared by a fellow student. This sample can be utilized as a research and reference resource to aid in the writing of your own work. Any use of the work that does not include an appropriate citation is banned.

If you are the owner of this work and don’t want it to be published on AssignBuster, request its removal.

Request Removal
Cite this Essay

References

AssignBuster. (2022) 'Apalutamide c21h15f4n5o2s structure'. 9 October.

Reference

AssignBuster. (2022, October 9). Apalutamide c21h15f4n5o2s structure. Retrieved from https://assignbuster.com/apalutamide-c21h15f4n5o2s-structure/

References

AssignBuster. 2022. "Apalutamide c21h15f4n5o2s structure." October 9, 2022. https://assignbuster.com/apalutamide-c21h15f4n5o2s-structure/.

1. AssignBuster. "Apalutamide c21h15f4n5o2s structure." October 9, 2022. https://assignbuster.com/apalutamide-c21h15f4n5o2s-structure/.


Bibliography


AssignBuster. "Apalutamide c21h15f4n5o2s structure." October 9, 2022. https://assignbuster.com/apalutamide-c21h15f4n5o2s-structure/.

Work Cited

"Apalutamide c21h15f4n5o2s structure." AssignBuster, 9 Oct. 2022, assignbuster.com/apalutamide-c21h15f4n5o2s-structure/.

More Related Papers
Trading factors
Vagueness causes for mislead voters in political campaigns
Tina turner’s comeback album: private dancer
Is complete certainty achievable in mathematics?
Product analysis of sprite
Get in Touch

Please, let us know if you have any ideas on improving Apalutamide c21h15f4n5o2s structure, or our service. We will be happy to hear what you think: [email protected]